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CANbridge Says C5 mAb Effective in Early Trial for Complement Diseases

publication date: Feb 7, 2022

CANbridge Pharma of Beijing reported positive data from a Singapore Phase I trial of its long-acting anti-C5 complement recombinant human mAb. CAN106 is a novel, long-acting mAb designed to neutralize C5, a key component of the complement system. In patients with paroxysmal nocturnal hemoglobinuria (PNH), division of C5 can cause cell lysis of red blood cells. The Phase I trial showed CAN106 to be well-tolerated while lowering levels of free C5 by 99%. CANbridge, a rare disease and oncology company, has also been approved to start CAN106 trials in China for PNH. More details....

Stock Symbol: (HK: 1228)

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