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Elpiscience Cleared for US Trials of Bispecific Immunotherapy in Solid Tumors

publication date: May 9, 2022

Shanghai Elpiscience was cleared to start US trials of a first-in-class bispecific antibody that targets two major immunosuppressive mechanisms in the tumor microenvironment. ES014 is an anti-CD39xTGF-β bispecific that simultaneously targets the CD39-adenosine and TGF-β pathways. Elpiscience will test the drug in patients with advanced solid tumors. An immunoncology company, Elpiscience now has five molecules in clinical trials including an CD39 monotherapy. One year ago, Elpiscience closed a $105 million Series C round to start US trials of its portfolio of 15 innovative molecules. More details....

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