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Sirnaomics to Start Clinical Trials of RNAi Candidate in China

publication date: Jun 17, 2021

Sirnaomics, a Maryland-Suzhou RNAi company, will add a China Phase IIb trial for its lead drug to the US trial, already underway. The company will test STP705, a siRNA (small interfering RNA) candidate that inhibits TGF-β1 and COX-2 gene expression in patients with skin squamous cell carcinoma (in situ). Sirnaomics uses its polypeptide nanoparticle (PNP)-enhanced technology to deliver the drug. The trial will enroll 100 adult patients with isSCC in five to seven clinical sites in the US and China. STP705 is also approved for testing in cholangiocarcinoma, non-melanoma skin cancer and hypertrophic scar. More details....

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